The howell•CR•III® is a unique wallet-style, child-resistant and senior-friendly compliance package for solid-dose pharmaceuticals. It is the optimal combination of economy of production, high-speed assembly, and F=1 rating. The howell•CR•III® has passed the Consumer Product Safety Commission's protocol at the highest level (F=1) for child resistance. Additionally, the package has been rated extraordinarily high (100%) in senior-friendliness. Applications include: compliance trade packages, patient starter kits, and patient titration units.